Publications

  • Leclerc S, Gupta A, Ruokolainen V, Chen JH, Kunnas K, Ekman AA, Niskanen H, Belevich I, Vihinen H, Turkki P, Perez-Berna AJ, Kapishnikov S, Mäntylä E, Harkiolaki M, Dufour E, Hytönen V, Pereiro E, McEnroe T, Fahy K, Kaikkonen MU, Jokitalo E, Larabell CA, Weinhardt V, Mattola S, Aho V, Vihinen-Ranta M. Progression of herpesvirus infection remodels mitochondrial organization and metabolism. PLoS Pathog. 2024 Apr 15;20(4):e1011829. doi: 10.1371/journal.ppat.1011829.
  • Ojha R, Jiang A, Mäntylä E, Modhiran M, Witte R, Arnaud G, De Zanetti Z, Gormal R, Vihinen-Ranta M, Mercer J, Suomalainen M, Greber U, Yamauchi Y, Yves-Lozac P, Helenius A, Vapalahti O, Young P, Daniel Watterson D, Meunier FA, Joensuu M, Balistreri G (2023).Alternative cell entry mechanisms for SARS-CoV-2 and multiple animal viruses. bioRxiv 2023.07.02.547368.
  • Salla Mattola, Simon Leclerc, Satu Hakanen, Moona Huttunen, Vesa Aho, Colin R Parrish, M. Vihinen-Ranta (2023), Parvovirus infection alters the nucleolar structure. bioRxiv 2022.06.07.495090.
  • Simon Leclerc, Alka Gupta, Visa Ruokolainen,Jian-Hua Chen, Kari Kunnas, Axel A. Ekman, Henri Niskanen, Ilya Belevich, Helena Vihinen, Paula Turkki, Ana J. Perez-Berna, Sergey Kapishnikov, Elina Mäntylä, Maria Harkiolaki, Eric Dufour, Vesa Hytönen, Eva Pereiro, Tony McEnroe, Kenneth Fahy, Minna U. Kaikkonen, Eija Jokitalo, Carolyn A. Larabell, Venera Weinhardt, Salla Mattola, Vesa Aho, Maija Vihinen-Ranta (2023). Progression of herpesvirus infection remodels mitochondrial organization and metabolism. bioRxiv 2023.11.16.567337.
  • Mäntylä E, Montonen T, Azzari L, Mattola S, Hannula M, Vihinen-Ranta M, Hyttinen J, Vippola M, Foi A, Nymark S, Ihalainen TO (2023)..Iterative immunostaining combined with expansion microscopy and image processing reveals nanoscopic network organization of nuclear lamina. Mol Biol Cell, 34(9):br13.
  • Leclerc S, Kunnas K, Ekman, Pereiro E3, Fahy K, Larabell C, Aho V, Weinhardt V, Vihinen-Ranta M (2023). Mitochondrial reorganization in herpesvirus-infected cell.Microscopy and Microanalysis, 29(S1): 1153–1154.
  • Parikka J, Heini Järvinen, Karolina Sokolowska, Visa Ruokolainen, Nemanja, Markešević, Ashwin Natarajan, Vihinen-Ranta M, Anton Kuzyk, Kosti Tapio, J. Jussi Toppari (2023). Creation of ordered 3D tubes using DNA origami lattices. Nanoscale 15, 7772-7780.
  • Mattola S, Salokas K, Aho V, Mäntylä E, Salminen S, Hakanen S, Niskanen EA, Svirskaite J, Ihalainen TO, Airenne KJ, Kaikkonen-Määttä M, Parrish CR, Varjosalo M, Vihinen-Ranta M (2022). Parvovirus nonstructural protein 2 interacts with chromatin-regulating cellular proteins. PloS Pathogens, 18(4): e1010353.
  • Mattola S, Mäntylä E, Aho V, Salminen S, Leclerc S, Oittinen M, Salokas K, Järvensivu J. Hakanen S, Ihalainen T. O, Viiri K, Vihinen-Ranta, M (2022). G2/M checkpoint regulation and apoptosis facilitate the nuclear egress of parvoviral capsids. Front Cell Dev Biol 10: 1070599.
  • Chen JH, Vanslembrouck B, Ekman A, Aho V, Larabell CA, Le Gros MA, Vihinen-Ranta M, Weinhardt V (2022). Soft X-ray Tomography Reveals HSV-1-Induced Remodeling of Human B Cells. Viruses 14: 2651.
  • Mattola S,Aho V, Bustamante-JaramilloLF, PizzioliE, Kann M, Vihinen-Ranta M (2022). Nuclear entry and egress of parvoviruses. Mol Microbiol 118:295-308.
  • Fadjukov J, Wienbar S, Hakanen S, Vihinen-Ranta M, Ihalainen TO, Schwartz GW and Nymark S (2022). Gap junctions and connexin hemichannels both contribute to the electrical properties of retinal pigment epithelium. J Gen Physiol 154 (4): e202112916.
  • XuM, PerdomoM, MattolaS, PyöriäL, ToppinenM, QiuJ, Vihinen-Ranta M, HedmanK,Nokso-KoivistoJ, AaltonenLM, and Söderlund-VenermoM (2021).  Characterization of human bocavirus 1 persistence in tonsillar tissues and antibody-dependent enhancement. mBio 12 (1) e03132-20.             
  • Fahy K, Weinhardt V, Vihinen-Ranta M, Skoko D, Fletcher E, Scholz D, Bartenschlager R, Ekman A, Gastaminza P, Pereiro E, McEnroe T (2021). Compact Cell Imaging Device – to provide insights into the cellular origins of viral diseases. J Phys Photonics 3(3):031002.
  • MattolaS, Hakanen S, SalminenS, AhoV, Mäntylä E, Ihalainen T, Kann M, Vihinen-Ranta M (2021). Concepts to reveal parvovirus-nucleus interactions. Viruses, 16;7(1): 3692.
  • Galibert L, Chafqane A, Eriksson RAE, Mattola S, Aho V, Salminen S, Peltola S, Albers JD, Weman S, Nieminen T, Ylä-Herttuala S, Lesch HP, Vihinen-Ranta M, Airenne KJ (2021). Functional properties of the adeno-associated virus encoded MAAP protein. Sci Rep 11(1): 21698.
  • Aho V, Salminen S, Mattola S,Gupta A, Flomm F, Sodeik B, Bosse JB,Vihinen-Ranta M (2021). Infection-induced chromatin modifications facilitate the translocation of herpes simplex virus capsids to the inner nuclear membrane. PloS Pathogens, 17(12): e1010132.
  • Mäntylä E, Aho V, Kann M, Vihinen-Ranta M (2020). Cytoplasmic parvovirus capsids recruit importin beta for nuclear delivery. J Virol 94: e01532-19.
  • Aho V, Mäntylä E, Ekman A, Hakanen S, Mattola S, Chen J-H, S, Weinhardt V, Ruokolainen V, Sodeik B, Larabell CA, and Vihinen-Ranta M (2019). Quantitative microscopy reveals stepwise alteration of chromatin structure during herpesvirus infection. Viruses, 11 (10): 935.
  • JohanssonJK, JokinenV, HakanenS, Jylhä A, Uusitalo H, Vihinen-Ranta M, SkottmanH, Ihalainen TO, Nymark S (2019). Fast voltage sensitivity in retinal pigment epithelium: sodium channels and their novel role in phagocytosis. BMC Biology 17(1):63.
  • Hildebrandt H, Paloheimo O, Mäntylä E, Willman S,Hakanen S, Albrecht K, Groll J, MöllerM and Vihinen-Ranta M (2018). Reactive Self-Assembly and Specific Cellular Delivery of NCO-sP(EO-stat-PO) Derived Nanogels. Macromol Biosci 18(7): 1800094.
  • Mäntylä E, Chacko J, Aho V, Di Rienzo C, Parrish CR, Kann M,Shahin V, Digman M, Gratton E, Vihinen-RantaM (2018). Viral highway to nucleus exposed by image correlation analyses. Sci Rep 8: 1152.
  • Mäntylä E, Kann M, Vihinen-Ranta M (2017). Parvovirus knocking at nuclear door. Viruses, 9(10): 286.
  • Pyöriä L, Toppinen M, Mäntylä E, Hedman L, Aaltonen L-M, Vihinen-Ranta M, Söderlund-Venermo M, Hedman K, Perdomo MF (2017). Extinct type of human parvovirus B19 persists in tonsillar B cells. Nat Commun 4(8): 14930.
  • Aho V, Myllys M, LarabellCA, Vihinen-RantaM (2017). Chromatin Reorganization during Viral Infection. Microscopy and Microanalysis 23(S1): 988.
  • Aho V, Myllys M, Ruokolainen V, Hakanen S, Mäntylä E,Virtanen J,Hukkanen V, Kühn T, Timonen J,Mattila K,Larabell C,and Vihinen-Ranta M (2017).Chromatin organization regulates viral egress dynamics. Sci Rep 7: 3692.

Funding